https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=8190
No pharmaceutical opinion available for this interaction.
Darunavir / ritonavir may induce the metabolism (UGT) and decrease the plasma concentration of Valproic acid (valproate, divalproex).
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Possible decrease of clinical efficacy.
Monitor for treatment response.
Adjust dosage if necessary.
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Valproic acid
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See valproic acid and lopinavir/ritonavir.