https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=19326
Document made available to the pharmacist to communicate a drug interaction to the doctor.
DOWNLOADLansoprazole by increasing gastric pH may decrease the solubility, absorption, and plasma concentration of velpatasvir .
Possible decrease of clinical efficacy.
Monitor for clinical efficacy.
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PPI doses should not exceed comparable to omeprazole 20 mg QD either dexlansoprazole 30 mg; esomeprazole 20 mg; lansoprazole 30 mg; pantoprazole 40 mg; rabeprazole 20 mg.
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See sofosbuvir/velpatasvir/voxilaprevir + omeprazole.