https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=14155
https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=14155
No pharmaceutical opinion available for this interaction.
Ritonavir may possibly induce the metabolism (CYP 2C9) and consequently decrease the concentration of Phenytoin.
Phenytoin may possibly induce the metabolism and decrease the plasma concentration of Ritonavir.
Possible decrease of clinical efficacy.
Monitor for signs and symptoms of therapeutic failure.
An increase in dosage may be necessary.
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Possible decrease of clinical efficacy.
Avoid if possible. Use an alternative or monitor patient closely.
Monitor for signs and symptoms of therapeutic failure.
An increase in dosage may be necessary.
Gabapentin, pregabalin, leviracetam.
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Associated PI plasma level
Phenytoin
CD4+
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