https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=13507
No pharmaceutical opinion available for this interaction.
Phenytoin can induce the metabolism (CYP 3A4) and decrease the plasma concentration of Cobicistat.
Possible decrease of the pharmacokinetic boosting effect.
Therefore, resulting in loss of therapeutic effect of associated IP.
Risk of a possible development of resistance to antiretroviral class.
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Contraindicated. Use alternative.
Gabapentin, pregabalin, leviracetam.
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Associated PI plasma level
Viral Load
CD4+
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