https://interactions.guidetherapeutiquevih.com/en/interaction-details?id=11776

Dolutegravir

Colestipol

Administration time adjustment is recommended.

No pharmaceutical opinion available for this interaction.

Mechanism

Colestipol can bind to other medicines administered simultaneously and decrease their absorption .

Dolutegravir

Pharmacodynamic effects

Possible decrease of clinical efficacy.

Recommendations

Take 1 hour before or 4 hours after taking colestipol.

Monitor for clinical efficacy.

Alternative solution(s)

–

Colestipol

Pharmacodynamic effects

–

Recommendations

–

Alternative solution(s)

–

Monitor

–

Tests

–

Pharmacokinetic parameters

–

Comment

Since colestipol may bind to other drugs given concomitantly, the product monograph recommends other drugs be taken at least one hour before, or four hours after, the taking of colestipol.

Reference
  • 2800
    Colestipol (Colestid), Pfizer, Quebec, Canada, 7 octobre 2013.